| Primary Identifier | MGI:2142347 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 243905 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription cis-regulatory region binding activity and transcription corepressor binding activity. Involved in embryonic placenta morphogenesis and negative regulation of transcription by RNA polymerase II. Acts upstream of or within convergent extension involved in axis elongation; convergent extension involved in neural plate elongation; and regulation of cell communication. Located in nucleus. Is expressed in several structures, including central nervous system; retina; and skeletal musculature. PHENOTYPE: Homozygous null mutants are embryonic lethal with growth arrest around E8.5-9.0. Mutant embryo shows shortened anterior-posterior axial extension with defects in somites and midline structures including open gut tube, cardia bifida, and failure to closeneural tube. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
