Primary Identifier | MGI:1316714 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 12865 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Contributes to cytochrome-c oxidase activity. Involved in oxidative phosphorylation. Located in mitochondrion. Part of respiratory chain complex IV. Is expressed in several structures, including aorta; brown fat; heart; lung; and metanephros. Used to study dilated cardiomyopathy. Orthologous to human COX7A1 (cytochrome c oxidase subunit 7A1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit some premature death and dilated cardiomyopathy. [provided by MGI curators] |