Primary Identifier | MGI:1913661 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 66411 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Predicted to be located in cytosol. Predicted to be active in cell cortex; microtubule plus-end; and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human TBCB (tubulin folding cofactor B). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts hatch from the zona pellucida but form irregular outgrowths after 3 days in culture. [provided by MGI curators] |