Primary Identifier | MGI:1891838 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 58206 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity; transcription corepressor activity; and zinc ion binding activity. Acts upstream of or within T cell proliferation; hemopoiesis; and regulation of cytokine production. Located in nuclear chromosome. Is expressed in alimentary system; genitourinary system; and respiratory system. Orthologous to human ZBTB32 (zinc finger and BTB domain containing 32). PHENOTYPE: Homozygous null mice display increased T cell proliferation and increased cytokine secretion. [provided by MGI curators] |