| Primary Identifier | MGI:98911 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 109637 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in epithelial cell differentiation. Located in apical plasma membrane. Is active in apical plasma membrane urothelial plaque. Is expressed in heart ventricle; lower urinary tract; lung; and rectum. Orthologous to human UPK1A (uroplakin 1A). PHENOTYPE: Male mice homozygous for a knock-out allele show a marginal reduction in fecundity associated with oligozoospermia, various histopathological changes in the male reproductive tract tissues as well as in non-reproductive tissues, and a lower bacterial clearance capacity in response to uropathogenic E. coli infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
