| Primary Identifier | MGI:2441731 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 233079 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled receptor activity. Involved in several processes, including leukocyte chemotaxis involved in inflammatory response; positive regulation of cytokine production; and regulation of insulin secretion. Is active in plasma membrane. Is expressed in pancreas; pancreas epithelium; superior cervical ganglion; and testis. Orthologous to human FFAR2 (free fatty acid receptor 2). PHENOTYPE: Mice homozygous for a null allele show altered granulocyte and neutrophil physiology and increased inflammation in models of induced colitis, arthritis and asthma, whereas homozygotes for a different null allele show reduced neutrophil recruitment and decreased susceptibility to induced colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
