Primary Identifier | MGI:2684079 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233081 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables bioactive lipid receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; ligand-gated ion channel signaling pathway; and positive regulation of transport. Acts upstream of or within insulin secretion. Located in plasma membrane. Is expressed in gut and male reproductive gland or organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FFAR1 (free fatty acid receptor 1). PHENOTYPE: There are conflicting reports on the metabolic affects of disrupting this gene. Glucose metabolism lipid levels have been studied. [provided by MGI curators] |