| Primary Identifier | MGI:1889273 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 56188 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sodium channel regulator activity. Involved in positive regulation of sodium ion export across plasma membrane; regulation of cardiac muscle cell membrane potential; and regulation of sodium ion transmembrane transporter activity. Located in sarcolemma. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and retina. Orthologous to human FXYD1 (FXYD domain containing ion transport regulator 1). PHENOTYPE: Adult mice homozygous for a knock-out allele exhibit cardiac hypertrophy, increased ejection fraction, and a 50% reduction in total Na-K-ATPase activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
