Primary Identifier | MGI:1916197 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 68947 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables N-acetylgalactosamine 4-O-sulfotransferase activity. Acts upstream of or within proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Is expressed in several structures, including foregut; genitourinary system; heart; nervous system; and pelvic girdle skeleton. Orthologous to human CHST8 (carbohydrate sulfotransferase 8). PHENOTYPE: Male mice homozygous for a null allele show higher luteinizing hormone and testosterone levels, early sexual maturation and enlarged seminal vesicles; females show higher LH, estrogen and progesterone levels, early sexual maturation, enlarged uteri, a prolonged estrous cycle and increased fecundity. [provided by MGI curators] |