| Primary Identifier | MGI:1915918 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 68668 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Predicted to be involved in several processes, including amelogenesis; extracellular matrix disassembly; and positive regulation of antibacterial peptide production. Predicted to be located in epidermal lamellar body. Predicted to be active in extracellular space and secretory granule. Is expressed in back skin. Orthologous to human KLK5 (kallikrein related peptidase 5). PHENOTYPE: Homozygous null mice show a modified commensal microbiome composition and impaired esophageal allergic inflammation, failing to increase esophageal eosinophilia in response to OVA challenge. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
