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Protein Coding Gene : Klk1b22 kallikrein 1-related peptidase b22
Primary Identifier  MGI:95291 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  13646
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables peptidase activity. Acts upstream of or within zymogen activation. Predicted to be located in acrosomal vesicle; apical part of cell; and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space and secretory granule. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1).
  • synonyms:
  • epidermal growth factor binding protein type A,
  • MGD-MRK-9316,
  • mGk-22,
  • Klk22,
  • MGD-MRK-9319,
  • Egfbp-1,
  • Klk1b22,
  • kallikrein 1-related peptidase b22,
  • kallikrein 22,
  • Egfbp1
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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