| Primary Identifier | MGI:1298219 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20256 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable growth factor activity. Predicted to be involved in ossification and positive regulation of cell population proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; head mesenchyme; renal vasculature; and retina nuclear layer. Orthologous to human CLEC11A (C-type lectin domain containing 11A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased bone volume in limb bones and vertebrae, reduced bone strength, and delayed fracture healing. Bone marrow stromal cells display impaired osteogenic differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
