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Protein Coding Gene : Clec11a C-type lectin domain family 11, member a

Primary Identifier  MGI:1298219 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  20256
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable growth factor activity. Predicted to be involved in ossification and positive regulation of cell population proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; head mesenchyme; renal vasculature; and retina nuclear layer. Orthologous to human CLEC11A (C-type lectin domain containing 11A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased bone volume in limb bones and vertebrae, reduced bone strength, and delayed fracture healing. Bone marrow stromal cells display impaired osteogenic differentiation. [provided by MGI curators]
  • synonyms:
  • stem cell growth factor,
  • expressed sequence AW457320,
  • C-type lectin domain family 11, member a,
  • Scgf,
  • Clecsf3,
  • AW457320,
  • Clec11a,
  • MGI:2142232

Features --> Cross References

Genome

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0 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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Literature

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1 Driver For