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Protein Coding Gene : Garin5a golgi associated RAB2 interactor 5A
Primary Identifier  MGI:1922788 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  75538
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in defense response to virus; innate immune response; and positive regulation of type I interferon production. Acts upstream of or within cell morphogenesis; single fertilization; and vacuole organization. Located in Golgi apparatus. Is active in sperm head. Orthologous to human GARIN5A (golgi associated RAB2 interactor 5A).
PHENOTYPE: Homozygous null males are subfertile, with impaired sperm motility, abnormal sperm head morphology, and impaired zona pellucida penetration during in vitro fertilization. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 0610007G24 gene,
  • 1700021N13Rik,
  • MGI:6885579,
  • Fam71e1,
  • MGI:1919501,
  • RIKEN cDNA 1700021N13 gene,
  • MGI:1925546,
  • golgi associated RAB2 interactor 5A,
  • 1700021P22Rik,
  • Garin5a,
  • RIKEN cDNA 1700021P22 gene,
  • 0610007G24Rik,
  • family with sequence similarity 71, member E1
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