| Primary Identifier | MGI:103017 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 14132 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable IgG binding activity and beta-2-microglobulin binding activity. Predicted to be involved in immune response. Predicted to be located in endosome and plasma membrane. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including genitourinary system; heart valve; intestine; sensory organ; and skeleton. Orthologous to human FCGRT (Fc gamma receptor and transporter). PHENOTYPE: Homozygous mutation of this gene results in defective perinatal transport of maternal IgG, increased clearance of IgG, and diminished IgG antibody response after immunization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
