| Primary Identifier | MGI:97381 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 78405 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable growth factor activity and nerve growth factor receptor binding activity. Involved in ameloblast differentiation. Acts upstream of or within several processes, including ganglion mother cell fate determination; long-term memory; and nervous system development. Predicted to be located in endoplasmic reticulum lumen and extracellular region. Predicted to be active in several cellular components, including axon; dendrite; and synaptic vesicle. Is expressed in brain; genitourinary system; and gut. Orthologous to human NTF4 (neurotrophin 4). PHENOTYPE: Nullizygous mice exhibit sensory neuron deficits. One nullizygous mutation causes loss of BDNF-dependent neural crest-derived sensory neurons and impaired coordination, while another leads to reduced neuron apoptosis, thick skin, and altered hair cycle control. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
