| Primary Identifier | MGI:1342299 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20174 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including ATPase binding activity; TFIID-class transcription factor complex binding activity; and adenyl ribonucleotide binding activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Part of ribonucleoprotein complex. Is expressed in several structures, including axial musculature; branchial arch; embryo mesenchyme; sensory organ; and viscerocranium. Orthologous to human RUVBL2 (RuvB like AAA ATPase 2). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality by E7.5. In vitro, blastocysts hatch from the zona pellucida but form irregular outgrowths with a poorly defined inner cell mass colony. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
