| Primary Identifier | MGI:98223 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20210 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Toll-like receptor 4 binding activity and chemoattractant activity. Involved in response to stilbenoid. Acts upstream of or within several processes, including I-kappaB phosphorylation; cell chemotaxis; and cellular response to interleukin-1. Located in extracellular space. Is expressed in several structures, including cerebellum; ileum; liver; reproductive system; and thymus. Orthologous to human SAA3P (serum amyloid A3, pseudogene). PHENOTYPE: Two chemically induced mutations result in prenatal lethality in homozygous mice. Mice homozygous for a knock-out allele exhibit reduced susceptibility to diet-induced obesity with improved lipid metabolism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
