Primary Identifier | MGI:94867 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 13172 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within regulation of transcription by RNA polymerase II and ventral spinal cord interneuron specification. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; future brain; head mesenchyme; urogenital ridge; and vertebral axis musculature. Orthologous to human DBX1 (developing brain homeobox 1). PHENOTYPE: Mice homozygous for disruptions of this gene die at birth. V0 interneurons develop as V1 or dl6 interneurons. [provided by MGI curators] |