| Primary Identifier | MGI:95657 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 14453 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity. Acts upstream of or within several processes, including ovarian follicle development; ovulation; and regulation of Notch signaling pathway. Predicted to be located in cytoplasm; membrane; and stress fiber. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and limb. Used to study sensorineural hearing loss. Orthologous to human GAS2 (growth arrest specific 2). PHENOTYPE: Null females have reduced fertility. Oocyte cyst breakdown is disrupted and follicle growth is impaired, with reduced antral follicle and corpora lutea numbers, and disrupted basal lamina surrounding follicles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
