| Primary Identifier | MGI:2158505 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 170711 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein K11-linked deubiquitination and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. Used to study chromosome 15q13.3 microdeletion syndrome. Orthologous to human OTUD7A (OTU deubiquitinase 7A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced body weight, abnormal spike wave discharge, decreased dendritic spine density, decreased prepulse inhibition, impaired coordination, decreased grip strength, decreased startle reflex, impaired ultrasonic vocalization and delayed tooth eruption. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
