Primary Identifier | MGI:2444486 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 272396 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables threonine-tRNA ligase activity. Involved in threonyl-tRNA aminoacylation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Orthologous to human TARS3 (threonyl-tRNA synthetase 3). PHENOTYPE: Homozygous null mice exhibit severe developmental retardation, elevated metabolic capacity, and abnormal bone and muscle development. [provided by MGI curators] |