| Primary Identifier | MGI:3646469 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 244071 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metallocarboxypeptidase activity and tubulin binding activity. Involved in C-terminal protein deglutamylation and protein side chain deglutamylation. Predicted to be located in cytosol. Predicted to be active in cytoplasm and microtubule cytoskeleton. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; liver; and retina. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy. Orthologous to human AGBL1 (AGBL carboxypeptidase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
