Primary Identifier | MGI:1888517 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 56315 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ammonium channel activity. Involved in ammonium transmembrane transport and regulation of pH. Located in apical plasma membrane. Is expressed in medulla oblongata basal plate ventricular layer; renal calyx; spinal cord ventricular layer; and telencephalon. Orthologous to human RHCG (Rh family C glycoprotein). PHENOTYPE: Mice homozygous for a null allele have reduced ability to excrete ammonium in their urine and have reduced male fertility. [provided by MGI curators] |