| Primary Identifier | MGI:1890505 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 103968 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within cellular response to cold and lipid catabolic process. Located in cytosol and lipid droplet. Is expressed in blood vessel and connective tissue. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 4 and obesity. Orthologous to human PLIN1 (perilipin 1). PHENOTYPE: Homozygous inactivation of this gene leads to increased lean body mass and altered adipocyte lipolysis, leptin production and susceptibility to diet-induced obesity. Increased oxygen and food consumption, impaired cold adaptation, and altered glucose andblood homeostasis have also been observed. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
