Primary Identifier | MGI:1338788 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 18631 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Acts upstream of or within brown fat cell differentiation. Predicted to be located in peroxisome. Predicted to be part of protein-containing complex. Predicted to be active in peroxisomal membrane. Orthologous to human PEX11A (peroxisomal biogenesis factor 11 alpha). PHENOTYPE: Mice homozygous for a knock-out allele exhibit minor abnormalities of the mitochondria and peroxisomes. Mice homozygous for a different knock-out allele exhibit increased body weight, hepatic steatosis and fewer, smaller peroxisomes in hepatocytes. [provided by MGI curators] |