Primary Identifier | MGI:5000466 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 16790 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metallopeptidase activity. Involved in angiotensin maturation. Is active in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and sensory organ. Orthologous to human ANPEP (alanyl aminopeptidase, membrane). PHENOTYPE: Mice homozygous for different knock-out alleles exhibit an increase in CD4+ thymocytes, altered macrophage adhesion, pathological neovascularization and/or altered mammary gland morphology during gestation. [provided by MGI curators] |