| Primary Identifier | MGI:1917711 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 70461 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cAMP response element binding protein binding activity and transcription coactivator activity. Involved in positive regulation of CREB transcription factor activity. Acts upstream of or within energy homeostasis; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway; and regulation of primary metabolic process. Located in cytoplasm and nucleus. Orthologous to human CRTC3 (CREB regulated transcription coactivator 3). PHENOTYPE: Mice homozygous for a null mutation display resistance to diet-induced obesity, increased energy expenditure, decreased white adipose tissue mass, increased brown adipose cell numbers, and increased core temperature. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
