Primary Identifier | MGI:1919218 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 71968 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cytoplasmic microtubule organization; negative regulation of apoptotic process; and nucleus organization. Predicted to colocalize with cleavage furrow; cytosol; and spindle pole. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 1. Orthologous to human WDR73 (WD repeat domain 73). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation. In vitro outgrowth assays show that blastocysts hatch from the zona pellucida but form irregular outgrowths. [provided by MGI curators] |