Primary Identifier | MGI:1920009 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72759 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of mitochondrial fission. Acts upstream of or within several processes, including regulation of oxidative phosphorylation; response to food; and retinal pigment epithelium development. Located in lipid droplet; mitochondrion; and peroxisome. Orthologous to human TMEM135 (transmembrane protein 135). PHENOTYPE: Mice homozgous for an ENU-induced allele exhibit age-dependent retinal pathologies. [provided by MGI curators] |