Primary Identifier | MGI:109126 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 21835 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables molecular function inhibitor activity and protein homodimerization activity. Involved in regulation of triglyceride biosynthetic process. Acts upstream of or within response to bacterium. Located in cytosol. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Used to study attention deficit hyperactivity disorder. Orthologous to human THRSP (thyroid hormone responsive). PHENOTYPE: Mice homozygous for a null allele exhibit decreased triglyceride during lactation and in milk produced as well as decreased de novo lipid biosynthesis in mammary tissue. [provided by MGI curators] |