Primary Identifier | MGI:1919840 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72590 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lncRNA binding activity. Involved in protein phosphorylation. Is expressed in several structures, including alimentary system; clavicle; ganglia; lower urinary tract; and nasal cavity epithelium. Orthologous to human PPME1 (protein phosphatase methylesterase 1). PHENOTYPE: Targeted disruption of this gene causes virtual loss of the demethylated form of phosphoprotein phosphatase 2A in the nervous system and peripheral tissues. Homozygous null mice fail to initiate normal breathing or suckling behavior and die within the first day of life. [provided by MGI curators] |