| Primary Identifier | MGI:106657 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20821 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to symbiont; protein ubiquitination; and regulation of DNA-binding transcription factor activity. Located in cytoplasm. Is expressed in central nervous system; genitourinary system; retina; and thymus primordium. Orthologous to human TRIM21 (tripartite motif containing 21). PHENOTYPE: Mice homozygous for a null allele display reduced survival and abnormal immune responses. Mice homozygous for a second null allele display increased salivation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
