| Primary Identifier | MGI:105112 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 15458 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heme binding activity. Acts upstream of or within several processes, including positive regulation of immune effector process; positive regulation of type II interferon-mediated signaling pathway; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to be active in extracellular space. Is expressed in brain; embryo; liver; liver left lobe; and liver right lobe. Orthologous to human HPX (hemopexin). PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. However, they have increased susceptiblity to induced hemolytic stress. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
