Primary Identifier | MGI:2651573 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 22141 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor binding activity and intraciliary transport particle A binding activity. Acts upstream of or within several processes, including phagocytosis, recognition; photoreceptor cell maintenance; and protein localization to non-motile cilium. Located in cytosol and extracellular region. Is expressed in several structures, including central nervous system; endocrine gland; musculature; peripheral nervous system; and sensory organ. Used to study obesity. Orthologous to human TUB (TUB bipartite transcription factor). PHENOTYPE: Homozygous mutants exhibit a late-developing obesity with hyperinsulinemia, retinal degeneration, and hearing loss associated with death of both outer and inner hair cells. [provided by MGI curators] |