Primary Identifier | MGI:3041226 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 57373 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within substrate adhesion-dependent cell spreading. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in nucleoplasm. Is expressed in genitourinary system; hippocampus; submandibular gland; and trachea. Orthologous to human AKIP1 (A-kinase interacting protein 1). PHENOTYPE: Mice homozygous for a null allele show lower thrombomodulin and fibrinogen levels, shorter prothrombin time and tail bleeding time, and lower mortality due to LPS challenge, when infected with the VP35 of Ebola virus. [provided by MGI curators] |