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Protein Coding Gene : Ipo7 importin 7
Primary Identifier  MGI:2152414 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  233726
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables histone binding activity. Involved in negative regulation of osteoblast differentiation; positive regulation of odontoblast differentiation; and positive regulation of protein localization to nucleus. Acts upstream of or within innate immune response and protein import into nucleus. Located in cytoplasm and nucleus. Orthologous to human IPO7 (importin 7).
PHENOTYPE: Mice homozygous for a knock-out allele show abnormal blastocyst morphology and complete embryonic lethality prior to organogenesis. [provided by MGI curators]
  • synonyms:
  • MGI:2442438,
  • RAN binding protein 7,
  • RanBP7,
  • Imp7,
  • RIKEN cDNA A330055O14 gene,
  • importin 7,
  • Ranbp7,
  • A330055O14Rik,
  • Ipo7
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2 Involved In Mutations

Trail: ProteinCodingGene

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