| Primary Identifier | MGI:1931144 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 57342 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin binding activity. Involved in several processes, including circulatory system development; smooth muscle cell chemotaxis; and substrate adhesion-dependent cell spreading. Acts upstream of or within cell adhesion. Located in several cellular components, including focal adhesion; lamellipodium; and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PARVA (parvin alpha). PHENOTYPE: Embryos homozygous for a null allele are growth retarded and die prior to E14.5 exhibiting abnormal cardiac morphogenesis, severe vascular defects, edema, microaneurysms, hemorrhage, and severe kidney dysgenesis or agenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
