| Primary Identifier | MGI:1927596 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 64297 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase binding activity and protein kinase inhibitor activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of neuron differentiation; and positive regulation of signal transduction. Acts upstream of or within several processes, including glucose homeostasis; positive regulation of neuron projection development; and positive regulation of protein kinase activity. Located in cell surface and membrane raft. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts. Orthologous to human GPRC5B (G protein-coupled receptor class C group 5 member B). PHENOTYPE: Mice homozygous for a reporter allele exhibit partial neonatal and postnatal lethality, altered spontaneous activity pattern, and decreased response to a new environment. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
