| Primary Identifier | MGI:1195271 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 11833 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ammonium channel activity; urea channel activity; and water channel activity. Involved in several processes, including ammonium import across plasma membrane; hydrogen peroxide transmembrane transport; and urea transport. Located in several cellular components, including intracellular canaliculus; mitochondrion; and smooth endoplasmic reticulum. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; liver; and submandibular gland primordium. Orthologous to human AQP8 (aquaporin 8). PHENOTYPE: Males homozygous for a null allele are fertile but show enlarged testes and reduced water permeability in testis plasma membranes. Females show increased ovulation, corpora lutea number and fertility, and a decrease in the plasma membrane water permeability and apoptosis rate of granulosa cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
