| Primary Identifier | MGI:1915919 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 381921 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neuropilin binding activity. Involved in neuron projection morphogenesis; positive regulation of JNK cascade; and regulation of actin cytoskeleton organization. Located in axonal growth cone and dendritic growth cone. Colocalizes with actin cytoskeleton. Is expressed in central nervous system and retina. Orthologous to human TAOK2 (TAO kinase 2). PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit decreased body size. Mice homozygous for a targeted allele exhibit resistance to the ataxic effect of alcohol, reduced blood ethanol content, increased alcohol consumption, impaired CPP for alcohol, and impaired habituation in an open field. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
