| Primary Identifier | MGI:105378 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 11489 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SH3 domain binding activity and metalloendopeptidase activity. Predicted to be involved in positive regulation of angiogenesis and proteolysis. Predicted to be located in nucleoplasm and plasma membrane. Is expressed in several structures, including bone; embryo mesenchyme; genitourinary system; gut; and meninges. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human ADAM12 (ADAM metallopeptidase domain 12). PHENOTYPE: Homozygous null mice display partial postnatal lethality, decreased brown fat, and impaired formation of neck and interscapular muscles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
