| Primary Identifier | MGI:1353653 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 30926 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and protein kinase C binding activity. Involved in negative regulation of cardiac muscle hypertrophy and regulation of the force of heart contraction. Located in Z disc. Is expressed in several structures, including brain; egg cylinder; genitourinary system; gut; and white fat. Orthologous to human GLRX3 (glutaredoxin 3). PHENOTYPE: Homozygotes for a gene trap allele die during late organogenesis/early fetal development with decreased embryo size, pericardial effusions and open anterior neural tubes. Homozygotes for a null allele show decreased embryo size, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
