| Primary Identifier | MGI:1915963 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 68713 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in negative regulation of viral entry into host cell and response to virus. Acts upstream of or within defense response to virus and somitogenesis. Predicted to be located in early endosome and lysosomal membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; embryo mesenchyme; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in adenosquamous gallbladder carcinoma and gallbladder adenocarcinoma. Orthologous to human IFITM1 (interferon induced transmembrane protein 1). PHENOTYPE: Homozygous mutant mice exhibited enhanced motor coordination during inverted screen testing when compared with that of their wild-type littermates. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
