Primary Identifier | MGI:2141847 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 101471 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase binding activity and protein domain specific binding activity. Predicted to be involved in mRNA processing and transcription by RNA polymerase II. Is expressed in several structures, including central nervous system and retina. Orthologous to human PHRF1 (PHD and ring finger domains 1). PHENOTYPE: Mice homozygous for a control allele activated in neurons exhibit Purkinje cell dendrite morphology, increased anxiety-related response, increased thigmotaxis, and impaired learning and memory. [provided by MGI curators] |