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Protein Coding Gene : Dusp8 dual specificity phosphatase 8

Primary Identifier  MGI:106626 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  18218
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables phosphatase activity. Involved in dephosphorylation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; placenta; retina; and yolk sac. Orthologous to human DUSP8 (dual specificity phosphatase 8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered myocardial fiber morphology, mildly increased cardiac muscle contractility at baseline, and decreased response of heart to induced stress. [provided by MGI curators]
  • synonyms:
  • neuronal tyrosine/threonine phosphatase 1,
  • Nttp1,
  • Dusp8,
  • AI593498,
  • MGI:2142006,
  • 5530400B01Rik,
  • expressed sequence AI593498,
  • MGD-MRK-35083,
  • dual specificity phosphatase 8,
  • RIKEN cDNA 5530400B01 gene,
  • MGI:1918684

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For