Primary Identifier | MGI:106626 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 18218 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatase activity. Involved in dephosphorylation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; placenta; retina; and yolk sac. Orthologous to human DUSP8 (dual specificity phosphatase 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered myocardial fiber morphology, mildly increased cardiac muscle contractility at baseline, and decreased response of heart to induced stress. [provided by MGI curators] |