| Primary Identifier | MGI:96832 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 16985 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity. Acts upstream of or within cellular response to interleukin-7; chemotaxis; and defense response. Predicted to be located in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; hair follicle; respiratory system; and thymus. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human LSP1 (lymphocyte specific protein 1). PHENOTYPE: Homozygotes for a targeted null mutation exhibit increased numbers of resident peritoneal macrophages and reduced numbers of peritoneal lymphocytes. Mutant neutrophils show abnormal morphology and impaired chemokine-induced migration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
