Primary Identifier | MGI:1888506 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 57264 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone activity. Predicted to be involved in several processes, including negative regulation of feeding behavior; positive regulation of cell communication; and positive regulation of smooth muscle cell proliferation. Located in extracellular space. Is expressed in adipose tissue. Human ortholog(s) of this gene implicated in hypertension; hypertrophic cardiomyopathy; obesity; and type 2 diabetes mellitus. Orthologous to human RETN (resistin). PHENOTYPE: Homozygous null mice display impaired gluconeogenesis, lower fasting blood glucose levels, and a weaker positive correlation between body weight and blood glucose. [provided by MGI curators] |