Primary Identifier | MGI:95497 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 14128 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including IgE binding activity; low-affinity IgE receptor activity; and protease binding activity. Acts upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin. Located in external side of plasma membrane. Is expressed in lymph node; spleen; and thymus. Orthologous to human FCER2 (Fc epsilon receptor II). PHENOTYPE: Mice homozygous for mutations in this gene are essentially normal although IgE levels or IgE mediated responses may be abnormal. [provided by MGI curators] |