| Primary Identifier | MGI:1923113 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 75863 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables polysaccharide binding activity. Acts upstream of or within negative regulation of T cell mediated immunity; negative regulation of alpha-beta T cell proliferation; and negative regulation of immature T cell proliferation in thymus. Located in plasma membrane. Orthologous to human CLEC4G (C-type lectin domain family 4 member G). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased intrahepatic T cell immunity, enhanced immune-mediated liver injury during Con A-induced experimental acute hepatitis, and accelerated CTL-dependent adenovirus clearance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
